Recombinant Human LRRTM2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3243
Recombinant Human LRRTM2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3243
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_056379.1 |
Background | Leucine-rich repeat transmembrane protein LRRTM2 as a key regulator of excitatory synapse development and function. LRRTM2 localizes to excitatory synapses in transfected hippocampal neurons, and shRNA-mediated knockdown of LRRTM2 leads to a decrease in excitatory synapses without affecting inhibitory synapses. LRRTM2 interacts with PSD-95 and regulates surface expression of AMPA receptors, and lentivirus-mediated knockdown of LRRTM2 in vivo decreases the strength of evoked excitatory synaptic currents. LRRTM2 induces only excitatory synapses, and that it also acts to induce synapses in transfected neurons similarly to neuroligin-1. |
Description | A DNA sequence encoding the human LRRTM2 (NP_056379.1) (Met1-Arg422) was expressed with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Cys 34 |
AA Sequence | Met1-Arg422 |
Molecular Weight | The recombinant human LRRTM2 consists of 400 a.a. and predicts a molecular mass of 46 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |