Recombinant Human LRP10 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3232
Recombinant Human LRP10 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3232
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | Q7Z4F1 |
Synonym | LRP9, MST087, MSTP087 |
Background | Various members of the low-density lipoprotein receptor (LDLR) family have been reported to play a role in APP trafficking and processing and are important risk factors in AD.LDLR-related protein 1 (LRP1) shuttles between the trans-Golgi Network (TGN), plasma membrane (PM), and endosomes.LRP1 is a functional APP receptor involved in APP trafficking and processing. LRP1 interacts directly with the ectodomain of APP and colocalizes with APP at the TGN. LRP1 is a novel APP sorting receptor that protects APP from amyloidogenic processing, suggesting that a decrease in LRP1 function may contribute to the pathogenesis of Alzheimer's disease. |
Description | A DNA sequence encoding the human LRP10 (Q7Z4F1-1) extracellular domain (Met 1-Lys 440) was fused with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | His 17 |
AA Sequence | Met 1-Lys 440 |
Molecular Weight | The secreted recombinant human LRP10/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 665 a.a. and has a predicted molecular mass of 73 kDa. The apparent molecular mass of rhLRP10/Fc monomer is approximately 80-90 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | >88% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |