Recombinant Human LILRA3 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3190
Recombinant Human LILRA3 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3190
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | AH28208.1 |
Synonym | CD85e, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4 |
Background | ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease. |
Description | A DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed, fused with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Gly 24 |
AA Sequence | Met1-Glu439 |
Molecular Weight | The recombinant human LILRA3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 657 a.a. and has a predicted molecular mass of 72 kDa. The apparent molecular mass of the protein is approximately 102 kDa in SDS-PAGE under reducing conditions. |
Purity | >80% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |