Recombinant Human KIR2DL3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3080
Recombinant Human KIR2DL3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3080
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | AAX23102.1 |
Synonym | CD158b, CD158B2, CU464054.1, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIR2DS5, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58 |
Background | Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-23GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, is a single-pass type I membrane protein which belongs to theimmunoglobulin superfamily. KIR2DL3 contains 2Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis. |
Description | A DNA sequence encoding the human KIR2DL3 (AAX23102.1) extracellular domain (Met 1-His 245) was fused with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | His 22 |
AA Sequence | Met 1-His 245 |
Molecular Weight | The secreted recombinant human KIR2DL3 consists of 235 a.a. and has a predicted molecular mass of 25.9 kDa. As a result of glycosylation, the apparent molecular mass of rh KIR2DL3 is approximately 45 kDa in SDS-PAGE under reducing conditions. |
Purity | >98% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |