Recombinant Human KAT3A (CREBBP) Protein

Beta LifeScience SKU/CAT #: BL-0175SG
Recombinant Human KAT3A (CREBBP) Protein

Recombinant Human KAT3A (CREBBP) Protein

Beta LifeScience SKU/CAT #: BL-0175SG
Catalog No.: BL-0175SG

Product Overview

Tag GST
Host Species Human
Accession NM_004380
Synonym CREBBP; CBP; RSTS
Background KAT3A has intrinsic histone acetyltransferase activity that acts as a scaffold to stabilize additional protein interactions with the transcription complex and acetylates both histone and non-histone proteins. KAT3A (CREBBP) expressed as a nuclear protein that binds to cAMP-response element binding protein (CREB) and involved in the transcriptional coactivation of many different transcription factors. KAT3A plays a main role in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition (1). KAT3A also plays a critical role in the transmission of inductive signals from cell surface receptors to the transcriptional apparatus (2).
Description Recombinant human KAT3A (CREBBP) (1319-1710) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1319-1710a.a.
Molecular Weight ~72 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human KAT3A (CREBBP) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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