Recombinant Human IL7 Protein
Beta LifeScience
SKU/CAT #: BL-1681SG
Recombinant Human IL7 Protein
Beta LifeScience
SKU/CAT #: BL-1681SG
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Accession | P13232 |
Synonym | IL-7, Recombinant Human Interleukin-7 (IL7) |
Background | IL7 is a secreted cytokine of the hemopoietin family that primarily affects early B and T cells and plays an important role in stimulating the proliferation of lymphoid progenitors. IL7 is produced by stromal epithelial cells of the thymus, bone marrow, and intestines. Human and murine IL7 share 60% sequence homology at the primary level and known to exhibit cross species activity. Designated CD127, the human IL7 receptor is a strongly glycosylated membrane protein of 76 kDa. Recombinant Human IL7 is a 17.7 kDa, non-glycosylated protein. |
Description | Recombinant Human IL7 was produced in E. coli. This protein is purified with our unique purification methods. |
Source | E.coli |
Molecular Weight | 17.7 kDa |
Purity | For specific purity information on a given lot, see related COA. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
Stability | The recombinant protein is stable for up to 12 months at -70°C |
Usage | For Research Use Only |
Storage | Recombinant Human IL7 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Target Details
Target Function | Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. |
Subcellular Location | Secreted. |
Protein Families | IL-7/IL-9 family |
Database References | HGNC: 6023 OMIM: 146660 KEGG: hsa:3574 STRING: 9606.ENSP00000263851 UniGene: PMID: 28845674 |