Recombinant Human IGSF3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2609
Recombinant Human IGSF3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2609
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | O75054 |
Synonym | EWI-3, LCDD, V8 |
Background | Immunoglobulin superfamily member 3 (IGSF3), also known as Glu-Trp-Ile EWI motif-containing protein 3, IgSF3 and EWI-3 and IGSF3, is a single-pass type I membrane protein which belongs to the EWI subfamily of the Ig Superfamily of molecules. IGSF3 has an overall structural similarity and strong sequence similarity to V7, a human leukocyte surface protein. IGSF3 contains eight Ig-like C2-type (immunoglobulin-like) domains. IGSF3 is expressed in a wide range of tissues with high expression in Placenta, kidney and lung. EWI-2 is part of a novel Ig subfamily that includes EWI-F (F2alpha receptor regulatory protein (FPRP), CD9P-1 ), EWI-3 (IGSF3), and EWI-11 (CD11). All four members of this Ig subfamily contain a Glu-Trp-Ile (EWI) motif not seen in other Ig proteins. Human IGSF3 shares 92 % aa identity with mouse IGSF3. |
Description | A DNA sequence encoding the human IGSF3 isoform 1 (O75054-1) extracellular domain (Met 1-Ala 1124) was expressed, with a C-terminal His tag. |
Source | HEK293 |
Predicted N Terminal | Gln 20 |
AA Sequence | Met 1-Ala 1124 |
Molecular Weight | The secreted recombinant human IGSF3 comprises 1116 a.a. and has a calculated molecular mass of 126.6 kDa. The apparent molecular mass of the recombinant protein is approximately 140 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | >98% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |