Recombinant Human HEMK2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2381
Recombinant Human HEMK2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2381
Catalog No.: BLPSN-2381
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | AAH11554.1 |
| Synonym | C21orf127, HEMK2, m.HsaHemK2P, MTQ2, N6AMT, PRED28 |
| Background | N6AMT1 has a significant role in determining susceptibility to arsenic toxicity and carcinogenicity because of its specific activity in methylating MMAIII to DMA and other unknown mechanisms.N6AMT1 polymorphisms were associated with arsenic methylation in Andean women, independent of AS3MT. N6AMT1 polymorphisms may be susceptibility markers for arsenic-related toxic effects.N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) also methylates the toxic inorganic arsenic (iAs) metabolite, monomethylarsonous acid (MMA), to the less toxic dimethylarsonic acid (DMA). |
| Description | A DNA sequence encoding the mature form of human N6AMT1 (AAH11554.1) (Met 1-Ser 186) was fused with a His tag at the C-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met 1 |
| AA Sequence | Met 1-Ser 186 |
| Molecular Weight | The recombinant human N6AMT1 comprises 196 a.a. and has a calculated molecular mass of 21.2 kDa. It migrates as an approximately 23 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 20mM Tris, pH 8.0. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
