Recombinant Human GBA/glucocerebrosidase Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2206
Recombinant Human GBA/glucocerebrosidase Protein (His Tag)

Recombinant Human GBA/glucocerebrosidase Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-2206
Catalog No.: BLPSN-2206

Product Overview

Tag His
Host Species Human
Accession NP_000148.2
Synonym GBA1, GCB, GLUC
Background Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD.
Description A DNA sequence encoding the human GBA (NP_000148.2) (Ala40-Gln536) was expressed with a His tag at the C-terminus.
Source HEK293
Predicted N Terminal Ala
AA Sequence Ala40-Gln536
Molecular Weight The recombinant human GBA consists of 508 a.a. and predicts a molecular mass of 57 kDa.
Purity >95% as determined by SDS-PAGE.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed