Recombinant Human Fucose Mutarotase Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2166
Recombinant Human Fucose Mutarotase Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2166
Catalog No.: BLPSN-2166
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | A2VDF0 |
| Synonym | C10orf125, FucM, FUCU |
| Background | FUOM, also known as fucose mutarotase and FucM, belongs to the RbsD / FucU family. FUOM is involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose has two isforms: alpha-L-fucose (29.5%) and beta-L-fucose (7.5%). The beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. FUOM mainly exists as homodimer, but also functions as homotetramer, homooctamer, and homodecamer. FUOM's homodimeric form seems catalytically inactive. |
| Description | A DNA sequence encoding the human C10orf125 (A2VDF0-1) (Met1-Leu154) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Leu154 |
| Molecular Weight | The recombinant human C10orf125 consists of 169 a.a. and predicts a molecular mass of 18.6 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
