Recombinant Human Frizzled 4 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-2145
Recombinant Human Frizzled 4 Protein (Fc Tag)

Recombinant Human Frizzled 4 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-2145

Product Overview

Tag Fc
Host Species Human
Accession NP_036325.2
Synonym CD344, EVR1, FEVR, Fz-4, Fz4, FZD4S, FzE4, GPCR, hFz4
Background Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR
Description A DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with the Fc region of human IgG1 at the C-terminus.
Source HEK293
Predicted N Terminal Phe 37
AA Sequence Met1-Glu180
Molecular Weight The recombinant human FZD4 consists 385 a.a. and predicts a molecular mass of 43.3 kDa.
Purity >95% as determined by SDS-PAGE.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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