Recombinant Human Frizzled 4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2145

Recombinant Human Frizzled 4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2145
Collections: Other recombinant proteins, Recombinant proteins
Product Overview
Tag | Fc |
Host Species | Human |
Accession | NP_036325.2 |
Synonym | CD344, EVR1, FEVR, Fz-4, Fz4, FZD4S, FzE4, GPCR, hFz4 |
Background | Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR |
Description | A DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Phe 37 |
AA Sequence | Met1-Glu180 |
Molecular Weight | The recombinant human FZD4 consists 385 a.a. and predicts a molecular mass of 43.3 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |