Recombinant Human FKBP7 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-2098
Recombinant Human FKBP7 Protein (Fc Tag)

Recombinant Human FKBP7 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-2098
Catalog No.: BLPSN-2098

Product Overview

Tag Fc
Host Species Human
Accession Q9Y680
Synonym FKBP23, PPIase
Background PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family, PPIL3 subfamily. PPIase contains 1 PPIase cyclophilin-type domain. Members of the immunophilin protein family play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It has a very high substrate specificity for the four-residue peptide Ala-Ala-Pro-Phe only when the proline peptide bond is in the trans state. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Description A DNA sequence encoding the human FKBP7 (Q9Y680-2) (Met1-Gln218) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Source HEK293
Predicted N Terminal Gln 24
AA Sequence Met1-Gln218
Molecular Weight The recombinant human FKBP7/Fc is a disulfide-linked homodimer. The reduced monomer comprises 436 a.a. and has a predicted molecular mass of 49.4 kDa. The apparent molecular mass of the protein is approximately 55kDa in SDS-PAGE under reducing conditions.
Purity >90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed