Recombinant Human ErbB3 / HER3 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0075NP
Recombinant Human ErbB3 / HER3 Protein (Fc Tag)

Recombinant Human ErbB3 / HER3 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0075NP
Catalog No.: BL-0075NP

Product Overview

Tag Fc
Host Species Human
Accession P21860
Synonym ErbB3 Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3
Background Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity.
Description Recombinant Human Receptor tyrosine-protein kinase ErbB-3 is expressed by our Mammalian expression system and the target gene encoding Ser20-Cys331 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Ser20-Cys331
Purity >90% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human ErbB3 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human ErbB3 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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