Recombinant Human EphA4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0010NP
Recombinant Human EphA4 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0010NP
Catalog No.: BL-0010NP
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | P54764 |
| Synonym | EphA4 Ephrin type-A receptor 4;HEK8; SEK; TYRO1;EPHA4;Tyrosine-protein kinase receptor SEK;Tyrosine-protein kinase TYRO1;EK8;hEK8;EPH-like kinase 8 |
| Background | Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
| Description | Recombinant Human Ephrin type A receptor 4 is expressed by our Mammalian expression system and the target gene encoding Val20-Thr547 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Val20-Thr547 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Measured by its ability to binding recombinant human Ephrin-A5 used funtional ELISA. The ED50 for this binding effect is 66.8nM when EphA4 2ug/ml in a solid phases. |
| Formulation | Recombinant Human EphA4 Protein was lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Human EphA4 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
