Recombinant Human EIF2AK4 (GCN2) Protein
Beta LifeScience
SKU/CAT #: BL-0351SG
Recombinant Human EIF2AK4 (GCN2) Protein
Beta LifeScience
SKU/CAT #: BL-0351SG
Catalog No.: BL-0351SG
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | NM_001013703 |
| Synonym | GCN2; KIAA1338 |
| Background | EIF2AK4 or eukaryotic translation initiation factor 2 alpha kinase 4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses (1). The EIF2AK4 eIF2-alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid (2). |
| Description | Recombinant human EIF2AK4 (192-1024) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | 192-1024 |
| Molecular Weight | ~132 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human EIF2AK4 (GCN2) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
