Recombinant Human EIF2AK4 (GCN2) Protein

Beta LifeScience SKU/CAT #: BL-0351SG
Recombinant Human EIF2AK4 (GCN2) Protein

Recombinant Human EIF2AK4 (GCN2) Protein

Beta LifeScience SKU/CAT #: BL-0351SG
Catalog No.: BL-0351SG

Product Overview

Tag GST
Host Species Human
Accession NM_001013703
Synonym GCN2; KIAA1338
Background EIF2AK4 or eukaryotic translation initiation factor 2 alpha kinase 4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses (1). The EIF2AK4 eIF2-alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid (2).
Description Recombinant human EIF2AK4 (192-1024) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 192-1024
Molecular Weight ~132 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human EIF2AK4 (GCN2) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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