Recombinant Human DYDC2 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1670
Recombinant Human DYDC2 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1670
Catalog No.: BLPSN-1670
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | Q96IM9 |
| Background | DPY3 domain containing 2 belongs to the dpy-3 family. Dumpy-3 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-3 (Dpy-3) of the worm C. elegans. Dpy-3 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY3 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY3 domain containing 2 may also play an indirect or direct role in endosomal transport. |
| Description | A DNA sequence encoding the mature form of human DYDC2 (Q96IM9) (Thr102-Pro176) was fused with the GST tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Thr102-Pro176 |
| Molecular Weight | The recombinant human DYDC2 /GST chimera consists of 307 a.a. and has a predicted molecular mass of 35.5 kDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >93% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
