Recombinant Human CYTL1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1541
Recombinant Human CYTL1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1541
Catalog No.: BLPSN-1541
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | NP_061129.1 |
| Synonym | C17, C4orf4 |
| Background | Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein.- Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1- expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is its only reported function in vivo. Despite lacking sequence homology to chemokines,- CYTL1is predicted by computational methods to fold like a chemokine, and has been reported to function as a chemotactic agonist at the chemokine receptor CCR2 in mouse monocyte/macrophages.- Recombinant CYTL1 promoted calcium flux in chondrocytes. Cytokine-like protein 1 (Cytl1), had been described as a protein expressed in CD34+ cells, and as a functional secreted protein involved in chondrogenesis and cartilage development. |
| Description | A DNA sequence encoding the human CYTL1 (NP_061129.1) (Met1-Arg136) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Thr 23 |
| AA Sequence | Met1-Arg136 |
| Molecular Weight | The recombinant human CYTL1 consists 348 a.a. and predicts a molecular mass of 39.8 kDa. |
| Purity | >90% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
