Recombinant Human Cystatin A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1527
Recombinant Human Cystatin A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1527
Catalog No.: BLPSN-1527
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | P01040 |
| Synonym | AREI, STF1, STFA |
| Background | Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family). |
| Description | A DNA sequence encoding the human CSTA (P01040) (Ile 2-Phe 98) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Ile 2-Phe 98 |
| Molecular Weight | The recombinant human CSTA consisting of 108 a.a. and has a calculated molecular mass of 12.4 KDa. It migrates as an approximately 14 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 50mM Tris, 1mM EDTA, pH 7.5. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
