Recombinant Human CNDP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1348
Recombinant Human CNDP2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1348
Catalog No.: BLPSN-1348
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | CAC69883.1 |
| Synonym | CN2, CPGL, HEL-S-13, HsT2298, PEPA |
| Background | Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to thepeptidase M2A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Itmay be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. |
| Description | A DNA sequence encoding the human CNDP2 (CAC69883.1) (Met 1-Asp 475) was expressed, fused with a His tag at the C-terminus. |
| Source | Baculovirus-Insect Cells |
| Predicted N Terminal | Met 1 |
| AA Sequence | Met 1-Asp 475 |
| Molecular Weight | The secreted recombinant human CNDP2 consists of 485 a.a. and predicts a molecular mass of 54.2 kDa as estimated in SDS-PAGE under reducing conditions. |
| Purity | >94% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, pH 8.0. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
