Recombinant Human CLEC10A Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1295
Recombinant Human CLEC10A Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1295
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | Q8IUN9 |
Synonym | CD301, CLECSF13, CLECSF14, HML, HML2, MGL |
Background | CLEC1A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD31) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD31 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD31a and CD31b) in mice. MGL1/CD31a induces both the production and secretion of interleukin (IL)-1. MGL1/CD31a plays a protective role against colitis by effectively inducing IL-1 production by colonic lamina propria macrophages in response to invading commensal bacteria. |
Description | A DNA sequence encoding the human CLEC10A (Q8IUN9-2) (Gln61-His292) was expressed, with the fused Fc region of human IgG1 at the N-terminus. |
Source | HEK293 |
Predicted N Terminal | Glu |
AA Sequence | Gln61-His292 |
Molecular Weight | The recombinant human CLEC10A/Fc is a disulfide-linked homodimer. The reduced monomer comprises 492 a.a. and has a predicted molecular mass of 54.6 kDa. The apparent molecular mass of the protein is approximately 58 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | >85% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |