Recombinant Human CEACAM5 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0155NP
Recombinant Human CEACAM5 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0155NP
Catalog No.: BL-0155NP
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | P06731 |
| Synonym | CEACAM5 Carcinoembryonic antigen-related cell adhesion molecule 5; CEACAM5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e |
| Background | Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell-cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker. |
| Description | Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 is expressed by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Lys35-Ala685 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Human CEACAM5 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Human CEACAM5 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
