Recombinant Human CART Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0584
Recombinant Human CART Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0584
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | NP_004282.1 |
Synonym | CART |
Background | In RNAseq data from human islet donors,- CARTPT- expression levels correlated with insulin, exocytosis genes and key beta-cell transcription factors.- Insufficient insulin release and hyperglucagonaemia are culprits in type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART, encoded by Cartpt) affects islet hormone secretion and beta cell survival in vitro in rats, and Cart (-/-) mice have diminished insulin secretion. Established a potential role for cocaine and amphetamine regulated transcript (CARTPT) in dominant follicle selection in cattle. CARTPT expression is elevated in subordinate versus dominant follicles, and treatment with the mature form of the CARTPT peptide (CART) decreases follicle-stimulating hormone (FSH)-stimulated granulosa cell estradiol production in vitro and follicular fluid estradiol and granulosa cell CYP19A1 mRNA in vivo. |
Description | A DNA sequence encoding the human CARTPT (NP_004282.1) (Met1-Leu116) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Gln 28 |
AA Sequence | Met1-Leu116 |
Molecular Weight | The recombinant human CARTPT/mFc comprises 323 a.a. and has a predicted molecular mass of 36.3 kDa. The apparent molecular mass of the monomer is approximately 37 kDa in SDS-PAGE under reducing conditions. |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |