Recombinant Human BTN3A2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0468
Recombinant Human BTN3A2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0468
Catalog No.: BLPSN-0468
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | NP_008978.2 |
| Synonym | BT3.2, BTF3, BTF4, BTN3.2, CD277 |
| Background | The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells.- BTN3A2- is overexpressed in gastric tumors, and deletion of- BTN3A2- inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence. |
| Description | A DNA sequence encoding the human BTN3A2 (NP_008978.2) (Met1-Trp248) was expressed with a His tag at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Gln 30 |
| AA Sequence | Met1-Trp248 |
| Molecular Weight | The recombinant human BTN3A2 consists of 230 a.a. and predicts a molecular mass of 25.1 kDa. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
