Recombinant Human Biglycan / BGN Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0403
Recombinant Human Biglycan / BGN Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0403
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_001702.1 |
Synonym | DSPG1, PG-S1, PGI, SLRR1A |
Background | Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity. |
Description | A DNA sequence encoding the human BGN (NP_001702.1) (Asp38-Lys368) was expressed with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Asp 38 |
AA Sequence | Asp38-Lys368 |
Molecular Weight | The recombinant human BGN consists of 342 a.a. and predicts a molecular mass of 38.7 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |