Recombinant Human BD1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-0388
Recombinant Human BD1 Protein (Fc Tag)

Recombinant Human BD1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-0388
Catalog No.: BLPSN-0388

Product Overview

Tag Fc
Host Species Human
Accession NP_005209.1
Synonym BD1, DEFB-1, DEFB101, HBD1
Background The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. One such strategy is to reduce the production of the antimicrobial peptide beta-defensin 1 (DEFB1) by host epithelial cells. Beta-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity.
Description A DNA sequence encoding the human DEFB1 (NP_005209.1) (Met1-Lys68) was expressed with the Fc region of human IgG1 at the C-terminus.
Source HEK293
Predicted N Terminal Gly 22
AA Sequence Met1-Lys68
Molecular Weight The recombinant human DEFB1 consists 285 a.a. and predicts a molecular mass of 31.8 kDa.
Purity >95% as determined by SDS-PAGE.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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