Recombinant Human BCL2L12 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0369
Recombinant Human BCL2L12 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0369
Catalog No.: BLPSN-0369
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | Q9HB09 |
| Background | BCL2-like 12 (BCL2L12 ) is a new member of the apoptosis-related BCL2 gene family, members of which are implicated in various malignancies. The mRNA expression of BCL2L12 may constitute a novel biomarker for the prediction of short-term relapse in nasopharyngeal carcinoma. BCL2L12 is a recently identified gene belonging to the BCL2 family, members of which are implicated in hematologic malignancies, including chronic lymphocytic leukemia (CLL). BCL2L12 can be considered as a new independent prognostic and chemotherapy response marker in AML. BCL2L12 mRNA expression may serve as a potential prognostic biomarker in tongue and/or larynx SCC, which principally constitute the great majority of HNSCC cases worldwide. BCL2L12 mRNA expression is a favorable prognostic marker of DFS for BC patients, suggesting its possible application as a novel prognostic indicator of this malignancy. |
| Description | A DNA sequence encoding the human BCL2L12 (Q9HB09-1) (Pro147-Lys227) was fused with the GST tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Pro147-Lys227 |
| Molecular Weight | The recombinant human BCL2L12/GST chimera consists of 314 a.a. and has a predicted molecular mass of 36 kDa. It migrates as an approximately 33 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 8.0.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
