Recombinant Human ARL2BP Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-0258
Recombinant Human ARL2BP Protein (His Tag)

Recombinant Human ARL2BP Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-0258
Catalog No.: BLPSN-0258

Product Overview

Tag His
Host Species Human
Accession Q9Y2Y0
Synonym BART, BART1, RP66
Background ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. ARL2BP, together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. ARL2BP may play a role as an effector of ARL2.
Description A DNA sequence encoding the mature form of human ARL2BP (Q9Y2Y0-1) (Met1-His163) was expressed with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal His
AA Sequence Met1-His163
Molecular Weight The recombinant human ARL2BP consists of 178 a.a. and predicts a molecular mass of 20.7 KDa. It migrates as an approximately 21 KDa band in SDS-PAGE under reducing conditions.
Purity >85% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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