Recombinant Human ARG1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0290NP
Recombinant Human ARG1 Protein (His Tag)

Recombinant Human ARG1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0290NP
Catalog No.: BL-0290NP

Product Overview

Tag His
Host Species Human
Accession P05089
Synonym ARG1 Arginase-1; Liver-type arginase; Type I arginase; ARG1
Background ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle, while it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.
Description Recombinant Human Arginase-1 is expressed by our Mammalian expression system and the target gene encoding Met1-Lys322 is expressed with a His tag at the C-terminus.
Source Human Cells
AA Sequence Met1-Lys322
Purity >90% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Bioactivity Measured by the production of urea during the hydrolysis of arginine. The specific activity is greater than 30000 pmol/min/µg.
Formulation Recombinant Human ARG1 Protein was supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 20% Glycerol, 1mMDTT, pH 7.4.
Usage For Research Use Only
Storage Human ARG1 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
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