Recombinant Human ARG1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0290NP
Recombinant Human ARG1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0290NP
Catalog No.: BL-0290NP
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | P05089 |
| Synonym | ARG1 Arginase-1; Liver-type arginase; Type I arginase; ARG1 |
| Background | ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle, while it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia. |
| Description | Recombinant Human Arginase-1 is expressed by our Mammalian expression system and the target gene encoding Met1-Lys322 is expressed with a His tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Met1-Lys322 |
| Purity | >90% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Measured by the production of urea during the hydrolysis of arginine. The specific activity is greater than 30000 pmol/min/µg. |
| Formulation | Recombinant Human ARG1 Protein was supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 20% Glycerol, 1mMDTT, pH 7.4. |
| Usage | For Research Use Only |
| Storage | Human ARG1 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. |
