Recombinant Human APOBEC4 Protein

Beta LifeScience SKU/CAT #: BL-3641PS
Recombinant Human APOBEC4 Protein

Recombinant Human APOBEC4 Protein

Beta LifeScience SKU/CAT #: BL-3641PS
Catalog No.: BL-3641PS

Product Overview

Tag N/A
Host Species Human
Synonym Apolipoprotein B MRNA Editing Enzyme, CatalyticPolypeptide-Like 4 (Putative), C1orf169, Apolipoprotein B MRNA-Editing EnzymeCatalytic Polypeptide-Like 4, Chromosome 1 Open Reading Frame 169, Putative C->U-EditingEnzyme APOBEC-4, EC 3.5.4.
Background APOBEC4belongs to the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases,which convert cytidine to uridine. Further AID/APOBEC family members areimplicated in Mrna editing, somatic hypermutation and recombination ofimmunoglobulin genes, and innate immunity to retroviral infection. Among thediseases associated with APOBEC4 are systemic lupus erythematosus, and lupuserythematosus.
Description APOBEC4 Human Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 390a.a. (1-367a.a.) and having a molecular weight of 44kDa.
Source E.coli
AA Sequence MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTEFCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRHIILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSGSHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSGQLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK
Purity >85% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation APOBEC4 protein solution (1mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Recently viewed