Recombinant Human Alpha SNAP / SNAPA Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0165
Recombinant Human Alpha SNAP / SNAPA Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0165
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_003818.2 |
Synonym | SNAPA |
Background | NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. Knockdown of NAPA using short-hairpin RNA was shown to induce p53 accumulation and to sensitize HEK293 cells to cisplatin. NAPA overexpression decreased the ubiquitination and degradation of synoviolin, and reduced p53 protein level.The combination of cisplatin and knockdown of NAPA represents a novel and attractive strategy to eradicate p53-sensitive cancer cells.NAPA-73 as one of the earliest neuronal markers may reflect a difference between the central and peripheral nervous systems. |
Description | A DNA sequence encoding the human NAPA (NP_003818.2) (Met1-Arg295) was expressed with a His tag at the N-terminus. |
Source | E.coli |
Predicted N Terminal | His |
AA Sequence | Met1-Arg295 |
Molecular Weight | The recombinant human NAPA consists 310 a.a. and predicts a molecular mass of 35 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | Please contact us for more information. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile 50 mM Tris, 10 % Glycerol, pH 8.0.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |