Recombinant Human AGR3 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0103
Recombinant Human AGR3 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0103
Catalog No.: BLPSN-0103
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | NP_789783.1 |
| Synonym | AG-3, AG3, BCMP11, hAG-3, HAG3, PDIA18 |
| Background | Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3- was found in breast, ovary, prostate, and liver cancer,- it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been characterised as a novel potential biomarker both for breast cancer prognosis and early breast cancer detection from blood. |
| Description | A DNA sequence encoding the human AGR3 (NP_789783.1) (Met1-Leu166) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Ile 22 |
| AA Sequence | Met1-Leu166 |
| Molecular Weight | The recombinant human AGR3 consists 379 a.a. and predicts a molecular mass of 43.4 kDa. |
| Purity | >85% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
