Recombinant Human AGA Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0100
Recombinant Human AGA Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0100
Catalog No.: BLPSN-0100
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | CAA39029.1 |
| Synonym | AGU, ASRG, GA |
| Background | S1 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S1 proteins, and the name is derived from the fact that the protein is1%soluble in ammonium sulfateat neutralpH. Most S1 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Human Protein S1-A8, also known as S1 calcium-binding protein A8, Cystic fibrosis antigen, Migration inhibitory factor-related protein 8, S1A8, and CAGA, is a member of the S-1 family. S1A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S1A9. S1A8 and S1A9 are known to be overexpressed in certain species of carcinomas. S1A8 plays an important role in dedifferentiation of thyroid carcinoma possibly by forming a complex with S1A9. S1A8 and S1A9 may also play a key role in inflammation-associated cancer. |
| Description | A DNA sequence encoding the human AGA (CAA39029.1) (Met1-Ile346) was expressed with a C-terminal His tag. |
| Source | HEK293 |
| Predicted N Terminal | Ser 24 |
| AA Sequence | Met1-Ile346 |
| Molecular Weight | The recombinant human AGA comprises 334 a.a. and has a predicted molecular mass of 36.1 kDa. The apparent molecular mass of the protein is approximately 47, 29, 23 and 20 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| Purity | (5.2+44.1+46.8+3.4)% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
