Recombinant DNA protection during starvation Protein
Beta LifeScience
SKU/CAT #: BLA-3614P
Recombinant DNA protection during starvation Protein
Beta LifeScience
SKU/CAT #: BLA-3614P
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Host Species | Helicobacter pylori |
Accession | P43313 |
Synonym | Bacterioferritin dps HP-NAP NAP A napA Neutrophil-activating protein A |
Description | Recombinant DNA protection during starvation Protein was expressed in E.coli. It is a Full length protein |
Source | E.coli |
AA Sequence | MKHHHHHHAS MKTFEILKHL QADAIVLFMK VHNFHWNVKG TDFFNVHKAT EEIYEEFADM FDDLAERIVQ LGHHPLVTLS EAIKLTRVKE ETKTSFHSKD IFKEILEDYK YLEKEFKELS NTAEKEGDKV TVTYADDQLA KLQKSIWMLQ AHLA |
Molecular Weight | 18 kDa |
Purity | >95% Densitometry. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Lyophilised |
Stability | The recombinant protein samples are stable for up to 12 months at -80°C |
Reconstitution | See related COA |
Unit Definition | For Research Use Only |
Storage Buffer | Shipped at 4°C. Store at -80°C. |
Target Details
Target Function | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. |
Subcellular Location | Cytoplasm. |
Protein Families | Dps family |
Database References | KEGG: heo:C694_01230 STRING: 85962.HP0243 |
Gene Functions References
- H. pylori NapA has unique and separate roles in gastric pathogenesis. PMID: 17030577