Recombinant Rat Glandular Kallikrein-7, Submandibular/Renal (KLK7) Protein (His)
Beta LifeScience
SKU/CAT #: BLC-10153P

Greater than 90% as determined by SDS-PAGE.
Recombinant Rat Glandular Kallikrein-7, Submandibular/Renal (KLK7) Protein (His)
Beta LifeScience
SKU/CAT #: BLC-10153P
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Rat Glandular Kallikrein-7, Submandibular/Renal (KLK7) Protein (His) is produced by our E.coli expression system. This is a full length protein. |
Purity | Greater than 90% as determined by SDS-PAGE. |
Uniprotkb | P36373 |
Target Symbol | KLK7 |
Synonyms | Klk7; Klk-7; Glandular kallikrein-7; submandibular/renal; rGK-7; EC 3.4.21.35; Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein |
Species | Rattus norvegicus (Rat) |
Expression System | E.coli |
Tag | N-6His |
Target Protein Sequence | VIGGYKCEKNSQPWQVALYSFTKYLCGGVLIDPSWVITAAHCSSNNYQVWLGRNNLLEDEPFAQHRLVSQSFPHPDYKPFLMRNHTRKPGDDHSNDLMLLHLSQPADITDGVKVIDLPTEEPKVGSTCLASGWGSTKPLIWEFPDDLQCVNIHLLSNEKCIKAYKEKVTDLMLCAGELEGGKDTCTGDSGGPLLCDGVLQGITSWGSVPCAKTNMPAIYTKLIKFTSWIKEVMKENP |
Expression Range | 25-261aa |
Protein Length | Full Length of Mature Protein |
Mol. Weight | 30.3kDa |
Research Area | Others |
Form | Liquid or Lyophilized powder |
Buffer | Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Reconstitution | Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Storage | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Target Details
Target Function | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney. |
Protein Families | Peptidase S1 family, Kallikrein subfamily |
Database References | |
Tissue Specificity | Kidney and submandibular gland. Not expressed in liver, pancreas, spleen, parotid, testis, cortex, prostate, ovary and pituitary. |
Gene Functions References
- Tissue kallikrein 1 and TIMP1 expressed in a coexpression vector synergistically inhibited the proliferation of rat vascular smooth muscle cells. PMID: 26252163
- Gonadectomy influences blood pressure through the kallikrein-kinin system. PMID: 19816038
- Klk7 rat gene was expressed at high levels in the submandibular glands of transgenic mice. PMID: 17366701
- Kal7 plays an essential role in synaptic structure and function, affecting a subset of cognitive processes. PMID: 19020030
- Plasma kallikrein levels are increased in the retina of rats with Ang II-stimulated hypertension. PMID: 19124682