Recombinant Mouse GPC1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0327NP
Recombinant Mouse GPC1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0327NP
Catalog No.: BL-0327NP
Product Overview
| Tag | His |
| Host Species | Mouse |
| Accession | Q9QZF2 |
| Synonym | GPC1 Glypican-1;Gpc1 |
| Background | Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. |
| Description | Recombinant Mouse Glypican-1 is expressed by our Mammalian expression system and the target gene encoding Asp24-Ser529 is expressed with a His tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Asp24-Ser529 |
| Purity | >90% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Measured by its ability to bind Human FGFb in functional ELISA. The ED50 for this effect is less than 10 ug/ml. |
| Formulation | Recombinant Mouse GPC1 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Mouse GPC1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
