Recombinant Mouse GPC1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0327NP
Recombinant Mouse GPC1 Protein (His Tag)

Recombinant Mouse GPC1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0327NP
Catalog No.: BL-0327NP

Product Overview

Tag His
Host Species Mouse
Accession Q9QZF2
Synonym GPC1 Glypican-1;Gpc1
Background Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.
Description Recombinant Mouse Glypican-1 is expressed by our Mammalian expression system and the target gene encoding Asp24-Ser529 is expressed with a His tag at the C-terminus.
Source Human Cells
AA Sequence Asp24-Ser529
Purity >90% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Bioactivity Measured by its ability to bind Human FGFb in functional ELISA. The ED50 for this effect is less than 10 ug/ml.
Formulation Recombinant Mouse GPC1 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Mouse GPC1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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