Name: Recombinant Mouse FGFRL1 Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-2086
Availability: InStock

Recombinant Mouse FGFRL1 Protein (His Tag)

Catalog No.: BLPSN-2086

Product Overview

Tag	His
Host Species	Mouse
Accession	NP_473412.1
Synonym	FGFRL1, FGFR5, FHFR, fibroblast growth factor receptor-like 1, fibroblast growth factor receptor like 1, FGFR-5
Background	Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene.FGFRL1 (Fibroblast Growth Factor Receptor Like 1) is a Protein Coding gene. Diseases associated with FGFRL1 include Wolf-Hirschhorn Syndrome and Vesicoureteral Reflux 1. Among its related pathways are Signaling by FGFR2 and mTOR signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include heparin binding and fibroblast growth factor-activated receptor activity. An important paralog of this gene is MCRIP2.
Description	A DNA sequence encoding the extracellular domain of mouse FGFRL1 (Met 1-Pro 374) precursor was expressed, with a C-terminal His tag.
Source	HEK293
Predicted N Terminal	Ala 21
AA Sequence	Met 1-Pro 374
Molecular Weight	The secreted recombinant mouse FGFRL1 consists of 365 amino acids and has a calculated molecular mass of 40.4 kDa. The apparent molecular mass of rmFGFRL1 is approximately 55-60 kDa in SDS-PAGE under reducing conditions.
Purity	>90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Measured by its binding ability in a functional ELISA.1. Immobilized mouse at 10 ug/ml (100 ul/well) can bind mouse FGFR5. The EC50 of mouse FGFR5 is 0.34 ug/ml.2. Immobilized human FGF1 at 10 ug/ml (100 ul/well) can bind mouse FGFR5 with a linear range of 0.08-2 ug/ml.3. Immobilized human bFGF at 5 ug/ml (100 ul/well) can bind mouse FGFR5. The EC50 of mouse FGFR5 is 0.22 ug/ml.
Formulation	Recombinant Mouse FGFRL1 Protein (His Tag) was lyophilized from sterile PBS, pH 7.4
Stability	Recombinant Mouse FGFRL1 protein is stable up to 1 year at -70°C
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.