Recombinant Human Uteroglobin (SCGB1A1) Protein
Beta LifeScience
SKU/CAT #: BL-1734SG
Recombinant Human Uteroglobin (SCGB1A1) Protein
Beta LifeScience
SKU/CAT #: BL-1734SG
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Accession | P11684 |
Synonym | Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, Urine protein 1, UP1 |
Background | UP1 is a non-glycosylated secretoglobin family member protein which induces anti-inflammatory and anti-tumorigenic responses. The expression of Uteroglobin is induced by steroid hormones such as estrogen which is further enhanced by the non-steroid hormone prolactin. UP1 has been shown to induce growth stimulatory effects, sequester pro-inflammatory mediators and carcinogens and inhibit cell migration, cell invasion, platelet aggregation and T cell differentiation. |
Description | Recombinant Human Uteroglobin (SCGB1A1) was produced in E. coli. This protein is purified with our unique purification methods. |
Source | E.coli |
Molecular Weight | 8.2 kDa |
Purity | For specific purity information on a given lot, see related COA. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
Stability | The recombinant protein is stable for up to 12 months at -70°C |
Usage | For Research Use Only |
Storage | Recombinant Human Uteroglobin (SCGB1A1) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Target Details
Target Function | Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. |
Subcellular Location | Secreted. |
Protein Families | Secretoglobin family |
Database References | HGNC: 12523 OMIM: 192020 KEGG: hsa:7356 STRING: 9606.ENSP00000278282 UniGene: PMID: 29685782 |