Name: Recombinant Human RAC3 Protein
Brand: Beta LifeScience
SKU: BL-0195SG
Availability: InStock

Catalog No.: BL-0195SG

Product Overview

Tag	His
Host Species	Human
Accession	NM_005052
Synonym	None
Background	RAC3 is a GTPase which belongs to the RHO family of small GTP-binding proteins that regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. RAC3 is primarily expressed in brain and is proposed to play a specific function in neuronal cells. Depletion of RAC3 induces stronger cell adhesion and dramatically increases the outgrowth of neurite-like protrusions whereas overexpression of RAC3 results in a contractile round morphology (1). RAC3 can exert its function through negatively affecting integrin-mediated cell-matrix adhesions (2). RAC3 shares with RAC1 the ability to interfere with cadherin-mediated adhesion.
Description	Recombinant full length human RAC3 was produced in E. coli, fused with a His tag at N-terminus.
Source	E.coli
AA Sequence	Full Length
Molecular Weight	24 kDa
Purity	For specific purity information on a given lot, see related COA.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Active
Formulation	Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability	The recombinant protein is stable for up to 12 months at -70°C
Usage	For Research Use Only
Storage	Recombinant Human RAC3 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.