Human PLOD3 (Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3) - Recombinant Protein
Beta LifeScience
SKU/CAT #: BLT-07692P
SDS-PAGE analysis of Human PLOD3 (Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3) - Recombinant Protein, CAT# BLT-07692P, showing >90% purity under 15% SDS-PAGE (Reduced)
Human PLOD3 (Multifunctional Procollagen Lysine Hydroxylase And Glycosyltransferase Lh3) - Recombinant Protein
Beta LifeScience
SKU/CAT #: BLT-07692P
Regular price
$69500
$695.00
Sale price$55600
$556.00Save $139
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Quantity Pricing
| Pack Size | Price (USD) |
|---|---|
| 500 µg | $1,206.00 Original price: |
| 1 mg | $2,284.00 Original price: |
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Product Overview
| Product Name | Recombinant Human Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3) Protein |
| Product Overview | This recombinant human Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3) protein includes amino acids 647-738aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id | O60568 |
| Recommended Name | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 |
| Gene Name | PLOD3 |
| Synonyms | LH3; Lysyl hydroxylase 3 |
| Species | Human |
| Predicted Molecular Mass | 14 kDa |
| Expression System | E.coli |
| Expression Range | 647-738aa |
| Tag | N-6His |
| Purity | >90% |
| Formulation | Lyophilized |
| Buffer | PBS |
| Storage Condition | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction | Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications | Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area | Others |
| Target Function | Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine. Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues. Essential for normal biosynthesis and secretion of type IV collagens. Essential for normal formation of basement membranes. |
| Subcellular Location | Rough endoplasmic reticulum. Endoplasmic reticulum lumen. Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Secreted. Secreted, extracellular space. |
| Associated Diseases | Lysyl hydroxylase 3 deficiency (LH3 deficiency) |
| Tissue Specificity | Ubiquitous. Detected in heart, placenta and pancreas and at lower levels in lung, liver and skeletal muscle. |
