Recombinant Human PDIA3 Protein (C-6His)
Beta LifeScience
SKU/CAT #: BL-1448NP

BL-1448NP: Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Recombinant Human PDIA3 Protein (C-6His)
Beta LifeScience
SKU/CAT #: BL-1448NP
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human Protein Disulfide-Isomerase A3 is produced by our Mammalian expression system and the target gene encoding Ser25-Leu505 is expressed with a 6His tag at the C-terminus. |
Accession | P30101 |
Synonym | PDIA3 protein;Protein disulfide-isomerase A3;58 kDa glucose-regulated protein;Disulfide isomerase ER-60;ER protein 57 |
Gene Background | PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. |
Molecular Mass | 55.3 KDa |
Apmol Mass | 60 KDa, reducing conditions |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Purity | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
Biological Activity | Not tested |
Reconstitution | |
Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Usage | For Research Use Only |
Target Details
Subcellular Location | Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. |
Protein Families | Protein disulfide isomerase family |
Database References | HGNC: 4606 OMIM: 602046 KEGG: hsa:2923 STRING: 9606.ENSP00000300289 UniGene: PMID: 29305423 |