Recombinant Human NTAQ1 Protein (GST Tag)

Beta LifeScience SKU/CAT #: BL-0273NP
Recombinant Human NTAQ1 Protein (GST Tag)

Recombinant Human NTAQ1 Protein (GST Tag)

Beta LifeScience SKU/CAT #: BL-0273NP
Catalog No.: BL-0273NP

Product Overview

Tag GST
Host Species Human
Accession Q96HA8
Synonym NTAQ1 Protein N-terminal glutamine amidohydrolase;WDYHV1;Protein NH2-terminal glutamine deamidase;N-terminal Gln amidase;Nt(Q)-amidase;C8orf32; NTAQ1
Background Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Description Recombinant Human Protein N-terminal glutamine amidohydrolase is expressed by our E.coli expression system and the target gene encoding Met1-Cys205 is expressed with a GST tag at the N-terminus.
Source E.coli
AA Sequence Met1-Cys205
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human NTAQ1 Protein was supplied as a 0.2 μm filtered solution of PBS, 100mM GSH, 1% TritonX-100, 15% Glycerol, pH 7.4.
Usage For Research Use Only
Storage Human NTAQ1 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
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