Recombinant Human NTAQ1 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BL-0273NP
Recombinant Human NTAQ1 Protein (GST Tag)
Beta LifeScience
SKU/CAT #: BL-0273NP
Catalog No.: BL-0273NP
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | Q96HA8 |
| Synonym | NTAQ1 Protein N-terminal glutamine amidohydrolase;WDYHV1;Protein NH2-terminal glutamine deamidase;N-terminal Gln amidase;Nt(Q)-amidase;C8orf32; NTAQ1 |
| Background | Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine. |
| Description | Recombinant Human Protein N-terminal glutamine amidohydrolase is expressed by our E.coli expression system and the target gene encoding Met1-Cys205 is expressed with a GST tag at the N-terminus. |
| Source | E.coli |
| AA Sequence | Met1-Cys205 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Human NTAQ1 Protein was supplied as a 0.2 μm filtered solution of PBS, 100mM GSH, 1% TritonX-100, 15% Glycerol, pH 7.4. |
| Usage | For Research Use Only |
| Storage | Human NTAQ1 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. |
