Recombinant Human NEK1 Protein

Beta LifeScience SKU/CAT #: BL-0020SG
Recombinant Human NEK1 Protein

Recombinant Human NEK1 Protein

Beta LifeScience SKU/CAT #: BL-0020SG
Catalog No.: BL-0020SG

Product Overview

Tag GST
Host Species Human
Accession NM_012224
Synonym ALS24; SRPS2; SRTD6; SRPS2A; NY-REN-55
Background NEK1 or NIMA (never in mitosis gene a)-related kinase 1 is a serine/threonine kinase involved in cell cycle regulation and is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. NEK1 is involved early in the DNA damage response pathway (1). In mice, NEK1 cycles through the nucleus via its nuclear localization and export signals (2). NEK1 protein participates in different signaling pathways to regulate diverse cellular processes and plays an important role in the kidney where it has opened a new avenue for studying cystogenesis and identifying possible modes of therapy (2).
Description Recombinant human NEK1 (1-477) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1-477
Molecular Weight 85 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human NEK1 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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