Recombinant Human IFNb1b Protein
Beta LifeScience
SKU/CAT #: BL-0493PS
Recombinant Human IFNb1b Protein
Beta LifeScience
SKU/CAT #: BL-0493PS
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Human |
Synonym | Leukocyte IFN, B cell IFN, Type I IFN, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956. |
Background | IFN-beta 1b has antiviral, antibacterial and anticancer activities. |
Description | IFN beta 1b Human Recombinant expressed in E.Coli is a single, non-glycosylated mutein (variant form) of human IFN beta-1b polypeptide chain containing 165a.a. and having a molecular weight of 18510.86 Dalton.The IFN-beta gene was cloned from human fibroblasts and altered to substitute Serine for the Cysteine residue found at position 17. IFN beta-1b is purified by unique purification methods. |
Source | E.coli |
AA Sequence | The sequence of the first five N-terminalaa was determined and was found to be Ser-Tyr-Asn-Leu-Leu. |
Purity | >98.0% as determined by:(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Bioactivity | The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 32 x 106 IU/mg. |
Formulation | Lyophilized from 1mg/ml solution containing 50mg Human Albumin & 50mg dextrose. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Lyophilized IFN-beta 1b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFNB 1b should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles. |