Recombinant Human HDAC9 Protein

Beta LifeScience SKU/CAT #: BL-0234SG
Recombinant Human HDAC9 Protein

Recombinant Human HDAC9 Protein

Beta LifeScience SKU/CAT #: BL-0234SG
Catalog No.: BL-0234SG

Product Overview

Tag GST
Host Species Human
Accession NM_058176
Synonym DKFZp779K1053; HD7; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; KIAA0744; MITR
Background HDAC9 or MITR belongs to the histone deacetylase /acuc/apha family and is a component of the histone deacetylase complex. HDAC9 gene is orthologous to the Xenopus and mouse MITR genes (MEF2-interacting transcription repressor). HDAC9 represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 is a calcium-sensitive transcriptional repressor of MEF2 (1). Binding of calmodulin to HDAC9 leads to its dissociation from MEF2, relieving MEF2 from the transcriptional repression. HDAC9 is a signal-responsive transcriptional repressor in mouse skeletal muscle that is downregulated upon denervation (2).
Description Recombinant human HDAC9 (548-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 548a.a.-end
Molecular Weight ~77 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human HDAC9 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed