Human CREBBP (Creb-Binding Protein) - Recombinant Protein

Beta LifeScience SKU/CAT #: BLT-07699P
SDS-PAGE analysis of Human CREBBP (Creb-Binding Protein) - Recombinant Protein, CAT
SDS-PAGE analysis of Human CREBBP (Creb-Binding Protein) - Recombinant Protein, CAT# BLT-07699P, showing >90% purity under 15% SDS-PAGE (Reduced)

Human CREBBP (Creb-Binding Protein) - Recombinant Protein

Beta LifeScience SKU/CAT #: BLT-07699P
Save $139
/
Size

Quantity Pricing

Pack Size Price (USD)
500 µg $1,206.00 Original price: $1,575.00
1 mg $2,284.00 Original price: $2,855.00

For direct online orders, quantity pricing will be displayed in cart when you add 5x100ug or 10x100ug


Submit an inquiry or email inquiry@betalifesci.com for a customization request or bulk order quote.

Connect with us via the live chat in the bottom corner to receive immediate assistance.

Product Overview

Product Name Recombinant Human CREB Binding (CREBBP) Protein
Product Overview This recombinant human CREB Binding (CREBBP) protein includes amino acids 2141-2442aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization.
Target Uniprot Id Q92793
Recommended Name CREB-binding protein
Gene Name CREBBP
Synonyms CBP; RSTS; RTS; KAT3A; Rubinstein-Taybi Syndrome
Species Human
Predicted Molecular Mass 37 kDa
Expression System E.coli
Expression Range 2141-2442aa
Tag N-6His
Purity >90%
Formulation Lyophilized
Buffer PBS
Storage Condition 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C.
Reconstitution Instruction Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%.
Applications Positive Control; Immunogen; SDS-PAGE; WB
Research Area Cancer
Target Function Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MAFG, NCOA3, POLR1E/PAF53 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER). Acetylates POLR1E/PAF53, leading to decreased association of RNA polymerase I with the rDNA promoter region and coding region. Acetylates DDX21, thereby inhibiting DDX21 helicase activity. Acetylates FBL, preventing methylation of 'Gln-105' of histone H2A (H2AQ104me). Functions as a transcriptional coactivator for SMAD4 in the TGF-beta signaling pathway.
Subcellular Location Cytoplasm. Nucleus. Note=Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.
Associated Diseases Rubinstein-Taybi syndrome 1 (RSTS1)

FAQs

Please fill out the Online Inquiry form located on the product page. Key product information has been pre-populated. You may also email your questions and inquiry requests to sales1@betalifesci.com. We will do our best to get back to you within 4 business hours.

Feel free to use the Chat function to initiate a live chat. Our customer representative can provide you with a quote immediately.

Proteins are sensitive to heat, and freeze-drying can preserve the activity of the majority of proteins. It improves protein stability, extends storage time, and reduces shipping costs. However, freeze-drying can also lead to the loss of the active portion of the protein and cause aggregation and denaturation issues. Nonetheless, these adverse effects can be minimized by incorporating protective agents such as stabilizers, additives, and excipients, and by carefully controlling various lyophilization conditions.

Commonly used protectant include saccharides, polyols, polymers, surfactants, some proteins and amino acids etc. We usually add 8% (mass ratio by volume) of trehalose and mannitol as lyoprotectant. Trehalose can significantly prevent the alter of the protein secondary structure, the extension and aggregation of proteins during freeze-drying process; mannitol is also a universal applied protectant and fillers, which can reduce the aggregation of certain proteins after lyophilization.

Our protein products do not contain carrier protein or other additives (such as bovine serum albumin (BSA), human serum albumin (HSA) and sucrose, etc., and when lyophilized with the solution with the lowest salt content, they often cannot form A white grid structure, but a small amount of protein is deposited in the tube during the freeze-drying process, forming a thin or invisible transparent protein layer.

Reminder: Before opening the tube cap, we recommend that you quickly centrifuge for 20-30 seconds in a small centrifuge, so that the protein attached to the tube cap or the tube wall can be aggregated at the bottom of the tube. Our quality control procedures ensure that each tube contains the correct amount of protein, and although sometimes you can't see the protein powder, the amount of protein in the tube is still very precise.

To learn more about how to properly dissolve the lyophilized recombinant protein, please visit Lyophilization FAQs.

More from All Products
Sale
SDS-PAGE analysis of Human USP9X (Ubiquitin Carboxyl-Terminal Hydrolase 9X) - Recombinant Protein, CAT# BLT-07739P, showing >90% purity under 15% SDS-PAGE (Reduced)
Human USP9X (Ubiquitin Carboxyl-Terminal Hydrolase 9X) - Recombinant Protein
  • Molecule: USP9X;
  • Species: Human;
  • Expression system: E.coli;
  • Tag: N-GST;
  • Sequence: 1554-1995aa;
CAT#: BLT-07739P

Save $139
Tn5 Transposase
  • Expression system: E.coli;
CAT#: TN5-BL01
Sale
SDS-PAGE analysis of Human TRIM21 (E3 Ubiquitin-Protein Ligase Trim21) - Recombinant Protein, CAT# BLT-07371P, showing >90% purity under 15% SDS-PAGE (Reduced)
Human TRIM21 (E3 Ubiquitin-Protein Ligase Trim21) - Recombinant Protein
  • Molecule: TRIM21;
  • Species: Human;
  • Expression system: E.coli;
  • Tag: N-6His;
  • Sequence: 268-465aa;
CAT#: BLT-07371P

Save $139
Sale
SDS-PAGE analysis of Human RECK (Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs) - Recombinant Protein, CAT# BLT-08901P showing >90% purity under 15% SDS-PAGE (Reduced)
Human RECK (Reversion-Inducing Cysteine-Rich Protein With Kazal Motifs) - Recombinant Protein
  • Molecule: RECK;
  • Species: Human;
  • Expression system: Mammalian Cell;
  • Tag: C-6His;
  • Sequence: 27-941;
CAT#: BLT-08901P

Save $139
Sale
SDS-PAGE analysis of Human SHFL (Shiftless Antiviral Inhibitor Of Ribosomal Frameshifting Protein) - Recombinant Protein, CAT# BLT-08873P showing >85% purity under 15% SDS-PAGE (Reduced)
Human SHFL (Shiftless Antiviral Inhibitor Of Ribosomal Frameshifting Protein) - Recombinant Protein
  • Molecule: SHFL;
  • Species: Human;
  • Expression system: E.coli;
  • Tag: N-6His+sumo;
  • Sequence: 1-291;
CAT#: BLT-08873P

Save $139
Sale
SDS-PAGE analysis of Human SFTPA1 (Pulmonary Surfactant-Associated Protein A1) - Recombinant Protein, CAT# BLT-08790P showing >90% purity under 15% SDS-PAGE (Reduced)
Human SFTPA1 (Pulmonary Surfactant-Associated Protein A1) - Recombinant Protein
  • Molecule: SFTPA1;
  • Species: Human;
  • Expression system: E.coli;
  • Tag: N-6His;
  • Sequence: 21-248;
CAT#: BLT-08790P

Save $139
Recently viewed