Recombinant Human CDC42 Protein

Beta LifeScience SKU/CAT #: BL-0192SG
Recombinant Human CDC42 Protein

Recombinant Human CDC42 Protein

Beta LifeScience SKU/CAT #: BL-0192SG
Catalog No.: BL-0192SG

Product Overview

Tag His&GST
Host Species Human
Accession NM_001791
Synonym G25K, CDC42Hs
Background CDC42 is a member of the Rho family of GTPases and is part of cellular pathways fundamental to growth, differentiation and apoptosis (1). Downstream targets for CDC42 include those that regulate the actin cytoskeleton (e.g. WASP) and cellular stress pathways (e.g. PAK) as well as the coatomer protein complex and PAR6. CDC42 is involved in the G(1)-S progression of the cell cycle. CDC42 and its downstream effector mDia3 are involved in bi-orientation and stabilization of spindle microtubules attachment to kinetochores and regulate chromosome alignment and segregation during mitosis (2).
Description Recombinant full length human CDC42 was produced in E. coli using an N-dual GST/His tag.
Source E.coli
AA Sequence Full Length
Molecular Weight ~48 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human CDC42 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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