Recombinant Human CD98 Protein (N-6His)
Beta LifeScience
SKU/CAT #: BL-2831NP

BL-2831NP: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Recombinant Human CD98 Protein (N-6His)
Beta LifeScience
SKU/CAT #: BL-2831NP
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human 4F2 Cell-surface Antigen Heavy Chain is produced by our Mammalian expression system and the target gene encoding Arg206-Ala630 is expressed with a 6His tag at the N-terminus. |
Accession | P08195 |
Synonym | 4F2 cell-surface antigen heavy chain; 4F2hc; SLC3A2; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2; MDU1; CD98 |
Gene Background | CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role. |
Molecular Mass | 47.7 KDa |
Apmol Mass | 58-80 KDa, reducing conditions |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Biological Activity | Not tested |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Usage | For Research Use Only |