Recombinant Human CA4 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0294NP
Recombinant Human CA4 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BL-0294NP
Catalog No.: BL-0294NP
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | P22748 |
| Synonym | CA4 Carbonic Anhydrase 4; Carbonate Dehydratase IV; Carbonic Anhydrase IV; CA-IV; CA4 |
| Background | Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris. |
| Description | Recombinant Human Carbonic Anhydrase 4 is expressed by our E.coli expression system and the target gene encoding Ala19-Lys283 is expressed with a His tag at the C-terminus. |
| Source | E.coli |
| AA Sequence | Ala19-Lys283 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Measured by its esterase activityThe Specific Activity is greater than 500 pmol/min/ug |
| Formulation | Recombinant Human CA4 Protein was supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, pH 8.5. |
| Usage | For Research Use Only |
| Storage | Human CA4 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. |
