Recombinant Human CA4 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0294NP
Recombinant Human CA4 Protein (His Tag)

Recombinant Human CA4 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0294NP
Catalog No.: BL-0294NP

Product Overview

Tag His
Host Species Human
Accession P22748
Synonym CA4 Carbonic Anhydrase 4; Carbonate Dehydratase IV; Carbonic Anhydrase IV; CA-IV; CA4
Background Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
Description Recombinant Human Carbonic Anhydrase 4 is expressed by our E.coli expression system and the target gene encoding Ala19-Lys283 is expressed with a His tag at the C-terminus.
Source E.coli
AA Sequence Ala19-Lys283
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Bioactivity Measured by its esterase activityThe Specific Activity is greater than 500 pmol/min/ug
Formulation Recombinant Human CA4 Protein was supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, pH 8.5.
Usage For Research Use Only
Storage Human CA4 protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
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