Recombinant Human AMSH Protein

Beta LifeScience SKU/CAT #: BL-0154SG
Recombinant Human AMSH Protein

Recombinant Human AMSH Protein

Beta LifeScience SKU/CAT #: BL-0154SG
Catalog No.: BL-0154SG

Product Overview

Tag His
Host Species Human
Accession NM_006463
Synonym STAMBP, MICCAP
Background AMSH (STAM binding protein) is a member of the JAMM metallo-enzyme family of deubiquitinating enzymes and is a ubiquitin isopeptidase found in the endosomes. It is involved in EGFR downregulation and regulates sorting of cell-surface receptors to the lysosome. The enzyme binds to the SH3 domain of STAM, which is required for MYC and cell growth (1). It has been hypothesized that mutations in AMSH are associated with Microcephaly-capillary malformation (2).
Description Recombinant full-length human AMSH was produced by baculovirus in Sf9 insect cells, fused with a His tag at N-terminus.
Source Sf9 insect cells
AA Sequence Full Length
Molecular Weight 54 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human AMSH Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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