Native Human Lactalbumin Protein
Beta LifeScience
SKU/CAT #: BAR-0111P
Native Human Lactalbumin Protein
Beta LifeScience
SKU/CAT #: BAR-0111P
Regular price$75300
$753.00
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Product Overview
| Description | α-Lactalbumin is an important whey protein in cow's milk, and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. ]α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme's affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase. |
| Source | Human Breast Milk |
| Form | Lyophilized Powder |
| Buffer | Lyophilized from de-ionized H2O |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Molecular Weight | 14 kDa |
| Protein Determination | Extinction Coefficient (E) = 1.82 (0.1% at 280 nm, 1 cm pathway) |
| Storage/Handling | ≤ -20°C |

